2022

Borg SÁ, Bork CS, Nielsen MRS, Jóanesarson J, Zaremba T, Lolas IBY et al. Subclinical atherosclerosis determined by coronary artery calcium deposition in patients with clinical familial hypercholesterolemia. Atherosclerosis Plus. 2022 dec.

Berhane T, Holm A, Karstensen KT, Petri A, Ilieva MS, Krarup H et al. Knockdown of the long noncoding RNA PURPL induces apoptosis and sensitizes liver cancer cells to doxorubicin. Scientific Reports. 2022 nov. 14;12(1):19502. PMID:36376362

Lau FF, Bollerup S, Engsig F, Krarup H, Mygind LH, Hansen JB et al. Ischemic Heart Disease in Chronic Hepatitis B: A Danish Nationwide Cohort Study. Clinical Epidemiology. 2022 jul.;14:879-888. PMID:35879942

Barnes DR, Silvestri V, Leslie G, McGuffog L, Dennis J, Yang X o.a. Breast and Prostate Cancer Risks for Male BRCA1 and BRCA2 Pathogenic Variant Carriers Using Polygenic Risk Scores. Journal of the National Cancer Institute. 2022 jan. 11;114(1):109-122. PMID:34320204

Blach S, Terrault NA, Tacke F, Gamkrelidze I, Craxi A, Tanaka J, et al. Global change in hepatitis C virus prevalence and cascade of care between 2015 and 2020: a modelling study. Lancet Gastroenterol Hepatol. 2022 05;7(5):396-415. PMID:35180382

Bollerup S, Hallager S, Engsig F, Mocroft A, Krarup H, Madsen LG et al. Mortality and cause of death in persons with chronic hepatitis B virus infection versus healthy persons from the general population in Denmark. Journal of Viral Hepatitis. 2022 maj 27. PMID:35633092

Bollerup S, Engsig F, Hallager S, Mocroft A, Roege BT, Christensen PB et al. Incidence of Hepatocellular Carcinoma and Decompensated Liver Cirrhosis and Prognostic Accuracy of the PAGE-B HCC Risk Score in a Low Endemic Hepatitis B Virus Infected Population. Journal of Hepatocellular Carcinoma. PMID:36281336:

Bor MV, Feddersen S, Pedersen IS, Sidelmann JJ, Kristensen SR. Dysfibrinogenemia-Potential Impact of Genotype on Thrombosis or Bleeding. Seminars in Thrombosis and Hemostasis. 2022;48(2):161-173. PMID:34261148

Dareng EO, Tyrer JP, Barnes DR, Jones MR, Yang X, Aben KKH o.a. Polygenic risk modeling for prediction of epithelial ovarian cancer risk. European Journal of Human Genetics. 2022 mar.;30(3):349-362. PMID:35027648

Frisk Toft CL, Diemer T, Ingerslev HJ, Pedersen IS, Adrian SW, Kesmodel US. Patients’ choices and opinions on chorionic villous sampling and non-invasive alternatives for prenatal testing following preimplantation genetic testing for hereditary disorders: A cross-sectional questionnaire study. Prenatal Diagnosis. 2022 feb.;42(2):212-225. PMID:34997771

Hakkaart C, Pearson JF, Marquart L, Dennis J, Wiggins GAR, Barnes DR et al. Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers. Communications Biology. 2022 okt. 6;5(1):1061. 1061. PMID:36203093:

Krarup KB, Rantanen JM, Mørk M, Pedersen IS, Christensen JH, Kristensen SR, et al. The Physiological and Cardiologic Effects of Long Video Gaming Sessions in Adult Males. Sports Med Int Open. 2022 Jan;6(1):E39-E46. PMID:35874049

Krarup HB, Rex KF, Andersen S. Mortality in Greenlanders with chronic hepatitis B virus infection. Journal of Viral Hepatitis. 2022 jun.;29(6):432-437. PMID:35357746

Li H, Engel C, de la Hoya M, Peterlongo P, Yannoukakos D, Livraghi L o.a. Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants. Genetics in Medicine. 2022 jan.;24(1):119-129. PMID:34906479

Li S, Silvestri V, Pedersen IS, Leslie G, Rebbeck TR, Neuhausen SL, Hopper JL o.a. Cancer Risks Associated With BRCA1 and BRCA2 Pathogenic Variants. Journal of Clinical Oncology. 2022 maj 10;40(14):1529-1541. JCO2102112. PMID:35077220

Michaelsen TY, Bennedbæk M, Christiansen LE, Jørgensen MSF, Møller CH, Sørensen EA, et al. Introduction and transmission of SARS-CoV-2 lineage B.1.1.7, Alpha variant, in Denmark. Genome Med. 2022 05 4;14(1):47. PMID:35505393

Møller KV, Nguyen HTT, Mørch MGM, Hesselager MO, Mulder FAA, Fuursted K et al. A Lactobacilli diet that confers MRSA resistance causes amino acid depletion and increased antioxidant levels in the C. elegans host. Frontiers in Microbiology. 2022 jul. 28;13. 886206. PMID:35966651

Møller P, Seppälä T, Dowty JG, Haupt S, Dominguez-Valentin M, Sunde L et al. Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium. Hereditary Cancer in Clinical Practice. 2022 okt. 1;20(1). 36. PMID:36182917

Offersgaard A, Duarte Hernandez CR, Finne Pihl A, Prabhakar Venkatesan N, Krarup H, Lin X o.a. High‐Titer Hepatitis C Virus Production in a Scalable Single‐Use High Cell Density Bioreactor. Vaccines. 2022 feb.;10(2). 249. PMID:35214707

Paulsen NH, Qvortrup C, Vojdeman FJ, Plomgaard P, Andersen SE, Ramlov A, et al. Dihydropyrimidine dehydrogenase (DPD) genotype and phenotype among Danish cancer patients: prevalence and correlation between DPYD-genotype variants and P-uracil concentrations. Acta Oncol. 2022 Nov;61(11):1400-5. PMID:36256873

Pihl AF, Feng S, Offersgaard A, Alzua GP, Augestad EH, Mathiesen CK o.a. Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice. Journal of Hepatology. 2022 maj;76(5):1051-1061. PMID:34990750

Popping S, Cento V, Seguin-Devaux C, Boucher CAB, de Salazar A, Heger E o.a. The european prevalence of resistance associated substitutions among direct acting antiviral failures. Viruses. 2022 jan.;14(1). 16. PMID:35062220

Thomassen M, Mesman RLS, Hansen TVO, Menendez M, Rossing M, Esteban-Sánchez A, et al. Clinical, splicing, and functional analysis to classify BRCA2 exon 3 variants: Application of a points-based ACMG/AMP approach. Hum Mutat. 2022 Dec;43(12):1921-44. PMID:35979650

Zheng W-Q, Pedersen SV, Thompson K, Bellacchio E, French CE, Munro B o.a. Elucidating the molecular mechanisms associated with TARS2-related mitochondrial disease. Human Molecular Genetics. 2022 feb.;31(4):523-534.PMID: 34508595