Cell culture as an alternative to whole genome amplification of DNA prior to preimplantation genetic testing (2018-2021)

Objective: 
To evaluate cell culture of biopsied trophectoderm cells as an alternative to whole genome amplifacation for preimplantation genetic testing. 

Design: 
Methods comparison study.

Cohort:
Patients receiving PGT for monogenic disorders and structural rearragenements.

Collaboration: 
Regenarative Medicine Group, Department of Health Science and Technology, Aalborg University, Denmark and Department of Informative Genetics, Tohoku University Graduate School of Medicine, Sendai, Japan.