Ph.d.-forløb

REPAIR-kuben har på tværs af afdelingerne syv tilknyttede ph.d.-forløb. På denne side kan du læse mere om projekterne, samt de ansvarlige ph.d.-studerende.

  • Simone Karlsson Terp, Department of Molecular Diagnostics
    Projekttitel: "Early detection of ovarian cancer and identification of genes affecting drug sensitivity in homologous recombination deficiency."
    Vejledere: Inge Søkilde Pedersen (AFMD/Aalborg UH), Karen Dybkær Sørensen (KI/Aalborg UH)

  • Jeannette Demant Andersen, Nuklearmedicinsk Afdeling
    Projekttitel: "Diagnostic accuracy when staging primary ovarian cancer with FDG PET/CT, prognostic value of semiquantitative PET-biomarkers and the value of FDG PET/CT in different subtypes of ovarian primary cancers; A retrospective study of approximately 1200 patients."
    Vejledere: Helle Zacho (Nuklearmedicinsk Afdeling), Aage (Knudsen Gynækologisk Afdeling)

  • Issa Ismail Issa, Dept of Clinical Medicine
    Projekttitel: "Targeting multidrug resistance mechanisms in Diffuse Large B-cell Lymphoma"
    Vejledere: Karen Dybkær (KI/Aalborg UH), Martin Bøgsted (KI/Clinda)

  • Hulda Haraldsdottir, Dept of Hematology
    Projekttitel: "DNA damage repair in Diffuse Large B-Cell Lymphoma and ovarian cancer: Diagnostic and prognostic tools for treatment strategy"
    Vejledere: Karen Dybkær (KI/AAUH), Inge Søkilde Pedersen (AFMD/Aalborg UH), Rasmus Brøndum (Aalborg UH)

  • Ida Burchard Egendal, Center for Clinical Data Science
    Projekttitel: "Mutational signatures using neural networks for robust stratification of cancer patients"
    Vejledere: Martin Bøgsted (KI/Clinda), Inge Søkilde Pedersen (AFMD/Aalborg UH), Karen Dybkær (KI/AAUH), Rasmus Brøndum (Aalborg UH)
  • Lasse Ringsted Mark, Department of Molecular Diagnostics
    Projekttitel: "Evaluation of homologous recombination deficiency detection algorithms on clinical data"
    Vejledere: Martin Bøgsted (KI/Clinda), Inge Søkilde Pedersen (AFMD/Aalborg UH)

  • Signe Bjerregaard Michelsen, Center for Clinical Data Science
    Projekttitel: "A new hybrid multimodal data fusion method to improving the prediction of response to platinum-based chemotherapy response in ovarian cancer"
    Vejledere: Martin Bøgsted (KI/Clinda), Charles Vesteghem (Clinda), Helle Zacho (Nuklearmedicinsk Afdeling), Lasse Riis Østergaard (Institut for Medicin og Sundhedsteknologi)

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Tillykke til Issa Ismail Issa med et vellykket ph.d.-forsvar!

Fra alle medlemmer af forskningsKUBEN REPAIR, skal der lyde et stort tillykke til Issa Ismail Issa, som fredag d. 17. maj med succes forsvarede sin ph.d. 

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FLOT STØTTE FRA NOVO NORDISK OG KRÆFTENS BEKÆMPELSE

Karen Dybkær, professor på Hæmatologisk Afdeling på Aalborg Universitetshospital, står i spidsen for to nye projekter, som skal undersøge genetiske variationer i en bestemt gruppe gener, der er relateret til reparation af DNA-skader i lymfeknudekræft. 

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Ny artikel - Homologous Recombination Deficiency Detection Algorithms, A Systematic Review

Simone Karlsson Terp skriver således om artiklen: "Our systematic review on Homologous Recombination Deficiency (HRD) Detection Algorithms has just been published! 📑 HRD, arising from genomic mutations or alterations in the homologous recombination repair pathway, holds significance in tumor treatment, especially in PARP inhibitor sensitivity. Our systematic review analyzed 27 articles, comparing tests for HRD detection based on diverse definitions, biomarkers, and algorithms The challenge? No established gold standard HRD test due to the lack of consensus on its definition. This review sheds light on the available tests, emphasizing the need for a standard definition crucial for accurate HRD classification."

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