Afskedsseminar for professor Øyvind Omland
På symposiet vil en række inviterede oplægsholdere samt Øyvind Omland selv præsentere resultater fra forskningen inden for det arbejds- og miljømedicinske område. Hør blandt andet risikofaktorer og forekomst af astma blandt landbrugsmedarbejdere (SUS-studiet), om aldringsprocesser i muskler og lunger samt om problemet med nedbrydningen af asbestholdige eternittage.
Symposiet afholdes fra kl. 13-15.45 på Aalborg Universitetshospital, Nord, Reberbansgade 15. Alle er velkomne.Program
13:00-13:10 Head of Department, Sigve W. Christensen and Professor Torben Sigsgaard: Welcome and introduction
13:10-13:40 Professor Torben Sigsgaard: What happened to the SUS study?
The SUS study has been running for more than 25 years studying the longitudinal effects of farm exposure on resoiratory health. The study has provided new insight into the respiratory diseases arising in young farmers, including new onset asthma and the effects on lung growth. One of the major findings have been the low sensitisation rate found among the farmers, and especially so in the persons born and raised on a farm with animals. From the start of the follow up there has been a strong focus on exposure assessment, and the SUS population has a rich dataset enabling the study of exposure respons fuctions. The extensive measuring campaigns has provided insight into the differences in farm operations of dust and endotoxin. During the last decade the focus has sifted towards genetic analyses of the participants and their interaction with the environment. A whole new era has developed in the exposure assessment, as the analses of the indoor microbiome in farms and non farm houses have been initiated, pointing to still new and unchartered research questions to be answered in the coming years.
13:40-14:10 Professor Martin Miller: Aging of the lungs
During life several age related changes in lungs and chest wall take place that influence the physiological capacity in humans. Age related reduction in lung elastic recoil leads to an increase in FRC with increased premature airway closure raising the RV. A concomitant increase in alveolar size gives a reason to raise the TLC but this is counterbalanced by age related reduction in muscle strength and reduced chest wall compliance. So TLC remains relatively unchanged whereas the reduction in muscle strength and chest wall compliance raise the RV even more. Increasingly after the age of 65 these age related changes in the lungs and thorax cavity reduce the efficiency of gas exchange and so may limit a person's ability to undertake strenuous work tasks. These changes in lung performance together with age related reduction in cardiac performance mean that in older subjects exercise capacity is significantly reduced and this may impact on their ability to undertake strenuous work tasks.
14:10-13:30 Coffe break
14:30-15:00 Professor Pascal Madeleine: Aging of the muscles
Ageing processes start already at the age of 30 years old. Despite a longer life expectancy, there are no sign of delay of ageing. Moreover, the current body of knowledge also emphasizes the discrepancy of being physically active at work and during leisure time. So what does ageing mean for manual workers aged 50-70 years and how are physical capacities affected?
The lecture will cover various aspects of physical capacities ranging from cardio-pulmonary fitness, dynamic, balance, force and upper limb coordination
15:00-15.30 Senior scientist Johnny Hansen: Is there anything more to know about asbetos related diseases?
It is well-documented that exposure to asbestos causes cancer of the lungs, larynx, ovary and mesothelioma. Further, there is some evidence that colorectal, pharynx and stomach cancer may be associated with asbestos. Previously, most focus has been on occupational exposures. Recent studies, however, have documented that even the neighborhood environment of asbestos product factories have an increased risk of mesothelioma. It is unclear whether this also may be the case for the other occupationally associated cancers.
Further, it has based on primarily case reports been suggested that also leukemia may be associated with asbestos exposure.
Finally, old asbestos still exist in the working environment as well as in private houses, and asbestos is still used in certain countries.
Thus, there are several reasons for still studying asbestos exposure and cancer.
15:30-15:45 Professor emeritus Øyvind Omland: Eternit roofs in Denmark: Should we worry for the environment?
More than 30 years ago in 1988, the last asbestos containing (10% w.) roof in Denmark was produced. Our best estimate is that round 1.3 mill. roofs still are cowered with asbestos containing tiles or plates. Data suggests that asbestos fibres are released from old tiles and plates due to decomposition and destruction. The degradation increases with age and exposure for water, ice, sun, wind, lav, mos, and pollution. The liberated asbestos fibres has been found with intact morphology and surface suggesting an intact biological characteristic including cancerogenic potential. The question to raise: Are we facing a potential serious asbestos air pollution, and if so, what are we going to do about it?
15:45-17:00 Reception
13:10-13:40 Professor Torben Sigsgaard: What happened to the SUS study?
The SUS study has been running for more than 25 years studying the longitudinal effects of farm exposure on resoiratory health. The study has provided new insight into the respiratory diseases arising in young farmers, including new onset asthma and the effects on lung growth. One of the major findings have been the low sensitisation rate found among the farmers, and especially so in the persons born and raised on a farm with animals. From the start of the follow up there has been a strong focus on exposure assessment, and the SUS population has a rich dataset enabling the study of exposure respons fuctions. The extensive measuring campaigns has provided insight into the differences in farm operations of dust and endotoxin. During the last decade the focus has sifted towards genetic analyses of the participants and their interaction with the environment. A whole new era has developed in the exposure assessment, as the analses of the indoor microbiome in farms and non farm houses have been initiated, pointing to still new and unchartered research questions to be answered in the coming years.
13:40-14:10 Professor Martin Miller: Aging of the lungs
During life several age related changes in lungs and chest wall take place that influence the physiological capacity in humans. Age related reduction in lung elastic recoil leads to an increase in FRC with increased premature airway closure raising the RV. A concomitant increase in alveolar size gives a reason to raise the TLC but this is counterbalanced by age related reduction in muscle strength and reduced chest wall compliance. So TLC remains relatively unchanged whereas the reduction in muscle strength and chest wall compliance raise the RV even more. Increasingly after the age of 65 these age related changes in the lungs and thorax cavity reduce the efficiency of gas exchange and so may limit a person's ability to undertake strenuous work tasks. These changes in lung performance together with age related reduction in cardiac performance mean that in older subjects exercise capacity is significantly reduced and this may impact on their ability to undertake strenuous work tasks.
14:10-13:30 Coffe break
14:30-15:00 Professor Pascal Madeleine: Aging of the muscles
Ageing processes start already at the age of 30 years old. Despite a longer life expectancy, there are no sign of delay of ageing. Moreover, the current body of knowledge also emphasizes the discrepancy of being physically active at work and during leisure time. So what does ageing mean for manual workers aged 50-70 years and how are physical capacities affected?
The lecture will cover various aspects of physical capacities ranging from cardio-pulmonary fitness, dynamic, balance, force and upper limb coordination
15:00-15.30 Senior scientist Johnny Hansen: Is there anything more to know about asbetos related diseases?
It is well-documented that exposure to asbestos causes cancer of the lungs, larynx, ovary and mesothelioma. Further, there is some evidence that colorectal, pharynx and stomach cancer may be associated with asbestos. Previously, most focus has been on occupational exposures. Recent studies, however, have documented that even the neighborhood environment of asbestos product factories have an increased risk of mesothelioma. It is unclear whether this also may be the case for the other occupationally associated cancers.
Further, it has based on primarily case reports been suggested that also leukemia may be associated with asbestos exposure.
Finally, old asbestos still exist in the working environment as well as in private houses, and asbestos is still used in certain countries.
Thus, there are several reasons for still studying asbestos exposure and cancer.
15:30-15:45 Professor emeritus Øyvind Omland: Eternit roofs in Denmark: Should we worry for the environment?
More than 30 years ago in 1988, the last asbestos containing (10% w.) roof in Denmark was produced. Our best estimate is that round 1.3 mill. roofs still are cowered with asbestos containing tiles or plates. Data suggests that asbestos fibres are released from old tiles and plates due to decomposition and destruction. The degradation increases with age and exposure for water, ice, sun, wind, lav, mos, and pollution. The liberated asbestos fibres has been found with intact morphology and surface suggesting an intact biological characteristic including cancerogenic potential. The question to raise: Are we facing a potential serious asbestos air pollution, and if so, what are we going to do about it?
15:45-17:00 Reception
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Kommunikationskonsulent
Publiceret af
Kommunikationskonsulent